时间：2026年9月22日（周二）上午9:00-10:00
Time：9:00-10:00, Tuesday, September 22nd, 2026
主持人: 西湖大学交叉科学中心讲席教授，钱紘博士
Host: Dr. Hong Qian, Chair Professor, Center for Interdisciplinary Studies (CIS)
地址：西湖大学云谷校区E14-349
Venue: E14-349, Yungu Campus, Westlake University
讲座语言：英文
Lecture Language: English
Dr. Sirui Ning（宁思睿）
Gordon and Betty Moore Foundation Postdoctoral Fellow
UC Berkeley, USA
主讲人/Speaker：
Dr. Sirui Ning received his DPhil in Theoretical Physics from the University of Oxford under the supervision of Prof. Joseph Conlon. He is currently a Gordon and Betty Moore Foundation Postdoctoral Fellow at UC Berkeley, working with Prof. Karthik Shekhar and Prof. Kranthi Mandadapu. His research lies at the intersection of membrane biophysics and theoretical neuroscience, using theory and computation to study bioelectricity, membrane electromechanics, and the physical mechanisms that connect ion channel activity to electrical signaling in neurons.
讲座摘要/Abstract:
Geometry plays a central role in electrophysiology by shaping how local ionic currents spread across cell membranes. Yet cells are often modeled using a single transmembrane voltage, assuming that they are electrotonically compact. Using theory and simulations of a spherical membrane vesicle driven by current through a single ion channel, I will examine when and how this approximation emerges.
At early times, the voltage response remains local and insensitive to the overall membrane geometry. Under sustained current, it spreads to the vesicle scale, where the finite and closed geometry drives a crossover to nearly uniform capacitive charging and a single membrane voltage. I will also introduce a nonlocal cable equation and identify the conditions under which conventional cable theory is recovered.
讲座联系人/Contact:
西湖大学交叉科学中心，朱子霖，邮箱：zhuzilin@westlake.edu.cn
Center for Interdisciplinary Studies (CIS), Westlake University, Ms. Zilin Zhu, Email: zhuzilin@westlake.edu.cn
